Autoimmunity is when the immune system cannot distinguish “self” from “non-self.” Some blood cells known as lymphocytes when turned on, are capable of reacting against self, resulting in an autoimmune reaction. Normally, these lymphocytes are suppressed because autoimmunity occurs naturally in everyone to some degree; and in most people, it does not result in diseases. Autoimmunity ensues when there is some interruption of the usual control process, allowing lymphocytes to avoid suppression, or when there is an alteration in some body tissue so that it is no longer recognized as “self” and is attacked. The exact mechanisms causing these changes are not completely understood; but environmental factors like bacteria, viruses, toxins, and some drugs may play a role in triggering an autoimmune process in someone who already has a genetic (inherited) predisposition to develop such a disorder. It is theorized that the inflammation initiated by these agents, toxic or infectious, somehow provokes in the body a “sensitization” (autoimmune reaction) in the involved tissues.

Autoimmune disease can be inherited among families from genetic predisposition.  Since genetics alone does not cause the development of autoimmune diseases, it is possible that autoimmune diseases present differently among family members. Also, other factors like toxins, poor diet, hormonal imbalance, infections and stress are usually present in order to trigger the disease process. It is important for families with members who have an autoimmune disease to mention this fact when another member of the family is experiencing medical problems that appear to be difficult to diagnose.

Autoimmunity is very unpredictable and not easy to identify. Many times it occurs over a long period of time without any sign of disease, however, there are usually several precursors that are telltale signs of autoimmunity. Examples: multiple food sensitivities, allergies, hormonal disruption, frequent infections and antibiotic use, skin problems and  non-specific unexplained symptoms.

No single test can diagnose most autoimmune diseases. A combination of tests and a review of symptoms and physical examination are the most common ways to reach a diagnosis. The antinuclear antibody test (ANA) is often the first marker doctors use when autoimmunity is suspected.

While there is no single cure to autoimmunity, a reversal of the disease process that leads to immune dysfunction responsible for associated symptoms is possible. This is known as remission.

Can I stop using prescription drugs like steroids if I achieve remission from autoimmunity?

Under strict medical supervision, steroids can be safely stopped when remission of autoimmunity is achieved.